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Cancer Center

Prostate Cancer: Risk Factors
When you’re told you have prostate cancer, it’s natural to wonder what may have caused the disease. No one knows the exact causes of prostate cancer. However, research has shown that men with certain risk factors are more likely than others to develop prostate cancer. A risk factor is something that may increase the chance of getting a disease.

Studies have found the following risk factors for prostate cancer:

  • Age over 65: Age is the main risk factor for prostate cancer. The chance of getting prostate cancer increases as you get older. In the United States, most men with prostate cancer are over 65. This disease is rare in men under 45.
  • Family history: Your risk is higher if your father, brother, or son had prostate cancer.
  • Race: Prostate cancer is more common among black men than white or Hispanic/Latino men. It’s less common among Asian/Pacific Islander and American Indian/Alaska Native men.
  • Certain prostate changes: Men with cells called high-grade prostatic intraepithelial neoplasia (PIN) may be at increased risk of prostate cancer. These prostate cells look abnormal under a microscope.
  • Certain genome changes: Researchers have found specific regions on certain chromosomes that are linked to the risk of prostate cancer. According to recent studies, if a man has a genetic change in one or more of these regions, the risk of prostate cancer may be increased. The risk increases with the number of genetic changes that are found. Also, other studies have shown an elevated risk of prostate cancer among men with changes in certain genes, such as BRCA1 and BRCA2.

Having a risk factor doesn’t mean that a man will develop prostate cancer. Most men who have risk factors never develop the disease.

Researchers are also studying the possible benefits of certain drugs, such as vitamin E, green tea extract, and other substances. These studies are with men who have not yet developed prostate cancer.

Prevent Cancer Foundation recommends men eat foods containing lycopene such as tomatoes, tomato products, red grapefruit, watermelon or apricots; and foods containing selenium such as light tuna, cod, beef, oatmeal, or whole wheat bread to reduce the risk of prostate cancer. They also recommend that you watch your intake of calcium because diets high in calcium may increase prostate cancer risk.