COVID-19 Clinical Trials & Research

Paving the way for progress, clinical trials are how we advance healthcare and ultimately, save more lives. Tallahassee Memorial HealthCare is proud to offer a national network of clinical trials for COVID-19 research in the Big Bend.

Activ-4: COVID-19 Outpatient Thrombosis Prevention Trial

Interested in Participating in a COVID-19 Study? Join Activ-4: COVID-19 Outpatient Thrombosis Prevention Trial

Tallahassee Memorial HealthCare (TMH) is part of a national effort to determine if blood thinners can help prevent blood clots that can cause strokes, pulmonary embolisms and deep vein thrombosis in COVID-19-positive people.

You may be eligible if:

  • You are having symptoms and have had a positive COVID-19 test within 14 days.
  • You are between the ages of 40 to 80.
  • You are not currently pregnant and can take blood thinners.

What to expect:

  • The study team will contact you to share more details about the study and determine if you would like to be screened and participate.
  • The study team will take a blood sample to see if you meet the study criteria.
  • If you meet the study criteria, you will be randomly selected to receive one of four medications to be taken for 45 days.
  • The FDA approved medication will be sent to your home and weekly follow-ups will take place by phone or email.

If interested, please contact TMH Office of Research at 850-431-4947 or CovidResearch@TMH.ORG.


HERO-TOGETHER Clinical Trial

The HERO-TOGETHER clinical trial is an opportunity for people working in healthcare who receive a COVID-19 vaccine to help the public understand how people do after vaccination. The COVID-19 pandemic is a once-in-a-generation challenge that healthcare heroes everywhere have worked together to face. From working on the front lines to working behind the scenes, people in healthcare and public service have joined together with unprecedented focus to fight COVID-19. Our healthcare heroes will continue to lead the way by being amongst the first to receive vaccines to protect against COVID-19.

What is involved?

  • Answer short surveys over the next two years about your health and any unexpected medical care received.
  • Receive compensation for your time.

Why participate?

  • Help researchers understand how different people — including men, women, older people, people with chronic diseases and people from different races and
    ethnic groups — do after vaccination.
  • Build confidence for vaccine use over time as we collect information about different people’s experiences.
  • It’s an easy way to help fight COVID-19 and learn how to keep our families healthy and virus free.

As we learn more about experiences from people like you who are vaccinated, researchers can learn how to best keep communities healthy and free of COVID-19.

How do I participate?

HERO-TOGETHER is available through the HERO Registry. If you are already a HERO member, you will receive an invitation to participate in the participant portal.

If you are not a HERO member, follow the below steps to join.

  1. Join the HERO Registry here.
  2. Complete the HERO-TOGETHER baseline surveys.


COVID-19 HERO Registry

The Healthcare Worker Exposure Response & Outcomes (HERO) Registry invites US healthcare workers to share their clinical and life experiences to help researchers understand the perspectives and problems faced by those on the frontlines of the COVID-19 pandemic. Tallahassee Memorial HealthCare (TMH) is one of the many healthcare organizations across the country participating in the HERO Registry.

How does it work?

You can use a work or personal email account to register online. The HERO registry is hosted on a secure, Google cloud account. Once on the registry website, you will click the “Join the Registry” green button to get started. Follow the prompts provided to setup a HERO registry account. After joining you will receive surveys, opportunities to participate in future studies and learnings from the HERO research community.

Who is eligible?

The HERO Registry is open to all healthcare workers, defined as anyone who works in a setting where people receive healthcare. This includes nurses, therapists, physicians, emergency responders, food service workers, environmental service workers, interpreters, transporters and others.

To register, please visit

For more information, please contact Kristin Herman at Kristin.Herman@TMH.ORG.